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Image Search Results
Journal: Nature protocols
Article Title: O 2 -controllable hydrogels for studying cellular responses to hypoxic gradients in three dimensions in vitro and in vivo
doi: 10.1038/nprot.2017.059
Figure Lengend Snippet: Subcutaneous and intramuscular in vivo oxygen sensing. Commercially available needle-type oxygen sensors (PreSens) were used to measure partial pressure of oxygen over time both (a) subcutaneously and (b) intramuscularly in 10- to 12-week-old nude mice. Sensors remained stationary and readings equilibrated after ~60 min to 7.4 and 3.0% in the subcutaneous and intramuscular regions, respectively. A temperature probe was used concomitantly to ensure the accuracy of the oxygen readings. The animal study was performed using a protocol (MO16A284) approved by The Johns Hopkins University Institutional Animal Care and Use Committee.
Article Snippet: Microx TX3 microfiber-optic oxygen transmitter; temperature-compensated system (PreSens)
Techniques: In Vivo